Natural pharmaceutical excipients have been applied extensively in the past decades owing to their safety and biocompatibility. Zein offers great benefit over other synthetic polymers used in controlled drug and biomedical delivery systems. It is used in a variety of medical fields including pharmaceutical and biomedical drug targeting, vaccine, tissue engineering, and gene delivery.
The good electrospinnability of zein is important for producing zein and zein-based nanofibers for applications in tissue engineering and drug delivery. The use of zein’s hydrolysate peptides for reducing blood pressure is another important issue related to the application of derivatives of zein in the biomedical field.